5-HTP

5-HTP (5-Hydroxytryptophan) is a compound the body uses in its serotonin production pathway, and one of the most searched single-ingredient supplements in the UK wellness space.

Choosing a format:

• Standard tablets and capsules — the most common format, from brands including Solgar, HealthAid and Lifeplan, in strengths typically ranging from 50mg to 100mg.
• Prolonged-release formulas — such as HealthAid's, designed to release gradually rather than all at once.
• Combination formulas — like Lifeplan's RelaxOn or Well Actually's Neuro Night, pairing 5-HTP with other ingredients.
• Gummies — Alpha01's format, for those who prefer not to take tablets or capsules.

Before you buy: 5-HTP has an important interaction with antidepressant medication that's essential to know about. Our FAQs below cover this and other key questions.